Deciphering the
Nano-World
Welcome to Xiaoji Xu's Research Group. We push the limits of Scanning Probe Microscopy and Infrared Spectroscopy to unravel nature's secrets at the nanoscale.
About Our Research
Microscopy opens many possibilities for understanding the composition, organization, and interaction of inhomogeneous materials. In our group, we develop variants of scanning probe microscopy (SPM) to study macromolecules, heterogeneous materials, and nanostructures to decipher their chemical, electrical, and mechanical properties.
One challenge of optical microscopy is Abbe's diffraction limit to about half of the wavelength (λ/2). Materials and structures often have nanometer-scale features much smaller than the diffraction limit—not directly resolvable by traditional optical microscopy. We work on atomic force microscopy (AFM)–based infrared (IR) and optical spectroscopy to bypass the diffraction limit, sometimes combined with ultrafast lasers or plasma emissions.

Core Techniques
Pioneering multimodal nanoscale imaging combining chemical, mechanical, and electrical characterization




Advanced optical and AFM instrumentation for nanoscale research

PFIR Microscopy
A SPM-based photothermal infrared microscopy with multimodal chemical/mechanical/electrical imaging capabilities

PF-KPFM
Ambient condition surface potential measurement with 10 nm spatial resolution

PFIR Applications
The PFIR microscopy has been applied across a wide range of samples for label-free chemical nano-imaging and spectroscopy

AFM-2DIR
We integrate AFM photothermal detection with femtosecond IR pulse sequence excitation to achieve action-based 2DIR spectroscopy without the restriction from Abbe's diffraction limit.

PF-SNOM
A new type of scattering near-field microscopy with direct three-dimensional response collections

s-SNOM Innovations
Innovations on methods to improve s-SNOM technique
Selected Publications
Research published in top-tier journals
Action-Based Two-dimensional Infrared Spectroscopy on the Horizon
Qing Xie and Xiaoji G. Xu
Kelvin probe force microscopy under ambient conditions
Amirhossein Zahmatkeshsaredorahi, Ruben Millan-Solsona, Devon S. Jakob, Liam Collins, and Xiaoji G. Xu
Atomic-force-microscopy-based time-domain two-dimensional infrared nanospectroscopy
Qing Xie, Yu Zhang, Eli Janzen, James H. Edgar, and Xiaoji G. Xu
The Group
Meet the researchers advancing nanoscale science

Xiaoji G. Xu
Professor
Genshuai Sun
PhD Student

Junlan Xu
MSc student
Join Us
We are actively seeking Ph.D. students and Postdocs to join our new lab at Stony Brook University!
Latest News
View All News →Xu Lab Moves to Stony Brook University
Starting from Jan. 2026, our research group will relocate to Stony Brook University. Exciting time ahead.
Dr. Xu Receives Richard P. Van Duyne Award
Dr. Xu received the Richard P. Van Duyne Early Career Award in Experimental Physical Chemistry, from American Chemical Society, Division of Physical Chemistry, 2025.
Contact Us
Mailing Address
Department of ChemistryStony Brook University
100 Nicolls Road
Stony Brook, NY, 11733
United States
Lab Location
5th Floor, Chemistry Building
Stony Brook University